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One of the owners of (239) 596-6968 is between 70-80 years old. We have records for 10 possible previous addresses for the owner, 12 other possible phone numbers, and 4 possible related persons connected to this individual.
Doctoral Thesis Title: “Oncogenic Disruption of the Transforming Growth Factor-Beta Signal Pathway.” A High Through-Put Screen was Designed to Detect Resistance to Tgf-Beta Induced Cell Growth Inhibition. A Fusion Protein Possessing A Fragment of the Group Antigen (Gag) Coding Sequence of the Retroviral Transfer Vector Fused in Frame to the Nuclear Orphan Receptor Ear2 (Erba Related 2). This Fusion Protein was Found to Share Significant Homology with the Known Oncogene V-Erba, and Expression of V-Erba was Sufficient to Antagonize Tgf-Beta Induced Growth Inhibition. Treatment of Cells Expressing V-Erba with the Hdac Inhibitor Trichostatin A (Tsa) was Sufficient to Restore Activity of A Pai-1 Promoter to Control Levels. These Findings Suggest That V-Erba Severely Represses Transcription of Tgf-Beta Activated Genes by Direct Association with the Tgf-Beta Pathway Member Smad4 Protein to Repress Transcriptional Activity Upon Formation of Histone Deacetylase Complexes. Show Less
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